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LATE Webinar Series, Part 3: Mixed Pathologies

Date: Friday, April 17, 2026
Time: 1:00 - 2:30 pm ET / 10:00 - 11:30 am PT 

About this Webinar:

Join us for the third and final webinar of the series on LATE (Limbic-Predominant Age-Related TDP-43 Encephalopathy)! Hear brief presentations on challenging clinical and pathologic cases and research updates from your colleagues across the ADRC network, with time for questions and discussion.

Topics will include neuropathology classification, mixed pathology, novel imaging and CSF biomarkers, and LATE mimics. With 6 presenters, the webinar will be supersized at 90 minutes. This webinar is hosted as a cross-core collaborative effort between the ADRC Clinical Core, Biomarker Core, Imaging Core, and Neuropathology Core Steering Committees.

Agenda:

• 10:00 am Introduction and Dr. Patrick Lao - Multimodal imaging signals of presumed Limbic-predominant age-related TDP-43 encephalopathy (LATE): A case study

• 10:15 am Dr. Emma Rhodes - Progressive amnestic syndrome in the absence of AD biomarkers and TDP-43 pathology

• 10:30 am Dr. Kathy Newell - Untangling, Postmortem, the Confounding Proteinopathies Coexisting with LATE-NC

• 10:45 am Dr. Peter Nelson - Case report with instructive combination of genetic, clinical, biomarker, and pathologic findings

• 11:00 am Dr. Ling Wu - New TDP-43 and p-tau tests for LATE detection and severity evaluation

• 11:15 am Erin Connolly - LATE-NC subtyping

• 11:30 am Conclusion

Featured Speakers:

Peter Nelson, MD, PhD 
Professor of Pathology; Neuropathology, Biomarker and Imaging Core Lead 
University of Kentucky, Sanders-Brown ADRC

Emma Rhodes, PhD 
Assistant Professor of Neurology 
University of Pennsylvania ADRC 

Kathy Newell, MD 
Professor of Pathology; Neuropathology Co-Core Leader 
Indiana ADRC  

Patrick Lao, PhD 
Assistant Professor of Neurological Sciences 
Columbia University Irving Medical Center, Columbia ADRC  

Erin Connolly, BS 
Brain Bank Laboratory Manager 
Duke/UNC ADRC

Ling Wu, MD, PhD 
Research Assistant Professor 
BRITE Institute of North Carolina Central University 

Aimee Pierce, MD - Moderator
Associate Professor of Neurology; Clinical Core Leader, Clinical Core Steering Committee Chair 
Oregon Health Sciences University ADRC 

How to Attend this Webinar:

Please register using the form on this page. Upon submission, you will receive a follow-up email with relevant event information, including the Zoom link and calendar invite. Please circulate this page to anyone who would like to join.

Questions?

Please reach out to info@naccdata.org with any questions regarding this webinar.